Visible-light-promoted divergent functionalizations of methylenecyclopropanes

Abstract

Simple and convenient visible-light-promoted radical monofunctionalization and difunctionalization of methylenecyclopropanes via ring-opening and cyclization processes have been developed for the syntheses of difluoromethyl compounds, alkyl compounds, halides, and sulfonyl compounds in moderate to excellent yields. The methodologies feature a wide substrate scope and tolerate various functional groups. A possible radical mechanism has been investigated and proven as a single electron transfer (SET) procedure.