Issue 16, 2021
From the journal:

Organic Chemistry Frontiers

Formation of diversified spiro-[imidazole-indene] derivatives from 2H-imidazoles: based on versatile propargyl alcohols†

Yi Luo,ab   Wei-Yi Pu,b   Yan-Jun Xu*a  and  Lin Dong ORCID logo *b  

* Corresponding authors

a College of Chemistry and Material Science, Sichuan Normal University, Chengdu, Sichuan 610066, China
E-mail: xuyj@sicnu.edu.cn

b Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry, West China School of Pharmacy, Sichuan University, Chengdu 610041, China
E-mail: dongl@scu.edu.cn

Abstract

Rh(III)-Catalyzed efficient cascade annulation for the regioselective construction of various spiro-[imidazole-indene] derivatives has been reported by utilizing versatile propargyl alcohols as coupling partners. The type of propargyl alcohol plays a key role in tuning the combination state and controlling formation of different products.

Graphical abstract: Formation of diversified spiro-[imidazole-indene] derivatives from 2H-imidazoles: based on versatile propargyl alcohols

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Article information

DOI
https://doi.org/10.1039/D1QO00629K
Article type
Research Article
Submitted
23 Apr 2021
Accepted
21 May 2021
First published
14 Jun 2021

Org. Chem. Front., 2021,8, 4549-4553

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Formation of diversified spiro-[imidazole-indene] derivatives from 2H-imidazoles: based on versatile propargyl alcohols

Y. Luo, W. Pu, Y. Xu and L. Dong, Org. Chem. Front., 2021, 8, 4549 DOI: 10.1039/D1QO00629K

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