Recent Progress in the Applications of Amino-yne Click Chemistry
Click chemistry has been rapidly developed in recent years. Among various classical or newly established click systems, spontaneous amino-yne click reaction stands out. In addition to the general advantages belonging to click reactions, it possesses extra merits, such as spontaneity of reactions, ubiquity of amines and cleavability of products with specific stimuli. Therefore, the amino-yne click reaction has provided easy access for scientists in various fields since its first report in 2017. In this review, we capture the very recent progress on the applications based on amino-yne click reaction, and the applications are classified and reviewed in the field of surface immobilization, designing for drug delivery, preparing hydrogel materials and synthesis of polymers with unique structures.