Issue 39, 2021

MeOTf/KI-catalyzed efficient synthesis of 2-arylnaphthalenes via cyclodimerization of styrene oxides

Abstract

The MeOTf/KI-catalyzed synthesis of 2-arylnaphthalene derivatives from aryl ethylene oxides in alcohol under ambient conditions is described. The present protocol has a higher atom efficiency and wider substrate applicability with excellent yields. The reaction proceeded using the aryl ethylene oxides to give 2-arylnaphthalenes either in homo-coupling or in cross-coupling. The reaction could also be carried out at the gram scale in minutes.

Graphical abstract: MeOTf/KI-catalyzed efficient synthesis of 2-arylnaphthalenes via cyclodimerization of styrene oxides

Supplementary files

Article information

Article type
Paper
Submitted
18 Aug 2021
Accepted
13 Sep 2021
First published
24 Sep 2021

Org. Biomol. Chem., 2021,19, 8559-8565

MeOTf/KI-catalyzed efficient synthesis of 2-arylnaphthalenes via cyclodimerization of styrene oxides

S. Zou, Z. Zhang, C. Chen and C. Xi, Org. Biomol. Chem., 2021, 19, 8559 DOI: 10.1039/D1OB01619A

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