Deep Eutectic Solvent Electrolysis for Preparing Water-Soluble Magnetic Iron Oxide Nanoparticles
Magnetic iron oxide nanoparticles have been proven versatile applications in biomedicine. Although numerous strategies have been developed to synthsize hydrophilic magnetic nanoparticles, it is still a challenge in quantity and controllability of preparation of highly dispersible, stably water-dispersive magnetic nanoparticles. The current work presents a deep-eutectic solvent electrolysis to synthesize magnetic nanoparticles. In the electrolysis process, iron atoms at anode electrode are oxidized to be ferric irons, and then the ions are combined with reactive oxygen species that derived from the decomposition of deep-eutectic solvents to form iron oxide nanocrystals. Concomitantly, hydrophilic radicals such as amino groups produced by electrolytes decomposition are grafted on the particles. The monodisperse nanoparticles size is ranged from 6 to 9 nm. The hydrophilic groups loaded nanoparticles can be highly dispersed in water with neither surface post-modification nor organic stabilizers. The hydrodynamic particle diameter is between 20 and 30 nm. The transparent aqueous dispersions can be maintained for more than 600 days without precipitation.