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Issue 3, 2021
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The chemistry and biology of guanidine secondary metabolites

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Abstract

Covering: 2017–2019

Guanidine natural products isolated from microorganisms, marine invertebrates and terrestrial plants, amphibians and spiders, represented by non-ribosomal peptides, guanidine-bearing polyketides, alkaloids, terpenoids and shikimic acid derived, are the subject of this review. The topics include the discovery of new metabolites, total synthesis of natural guanidine compounds, biological activity and mechanism-of-action, biosynthesis and ecological functions.

Graphical abstract: The chemistry and biology of guanidine secondary metabolites

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Article information


Submitted
16 Jul 2020
First published
06 Oct 2020

Nat. Prod. Rep., 2021,38, 586-667
Article type
Review Article

The chemistry and biology of guanidine secondary metabolites

R. G. S. Berlinck, D. I. Bernardi, T. Fill, A. A. G. Fernandes and I. D. Jurberg, Nat. Prod. Rep., 2021, 38, 586
DOI: 10.1039/D0NP00051E

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