Issue 3, 2021
From the journal:

Natural Product Reports

The chemistry and biology of guanidine secondary metabolites

Roberto G. S. Berlinck, ORCID logo *a   Darlon I. Bernardi, ORCID logo a   Taicia Fill, ORCID logo b   Alessandra A. G. Fernandesb  and  Igor D. Jurberg ORCID logo b  

* Corresponding authors

a Instituto de Química de São Carlos, Universidade de São Paulo, CP 780, São Carlos, SP, Brazil
E-mail: rgsberlinck@iqsc.usp.br

b Instituto de Química, Universidade Estadual de Campinas, Rua Monteiro Lobato 270, Campinas, SP, Brazil

Abstract

Covering: 2017–2019

Guanidine natural products isolated from microorganisms, marine invertebrates and terrestrial plants, amphibians and spiders, represented by non-ribosomal peptides, guanidine-bearing polyketides, alkaloids, terpenoids and shikimic acid derived, are the subject of this review. The topics include the discovery of new metabolites, total synthesis of natural guanidine compounds, biological activity and mechanism-of-action, biosynthesis and ecological functions.

Graphical abstract: The chemistry and biology of guanidine secondary metabolites

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Article information

DOI
https://doi.org/10.1039/D0NP00051E
Article type
Review Article
Submitted
16 Jul 2020
First published
06 Oct 2020

Nat. Prod. Rep., 2021,38, 586-667

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The chemistry and biology of guanidine secondary metabolites

R. G. S. Berlinck, D. I. Bernardi, T. Fill, A. A. G. Fernandes and I. D. Jurberg, Nat. Prod. Rep., 2021, 38, 586 DOI: 10.1039/D0NP00051E

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