Preparation of ionogel-bonded mesoporous silica and its application in liquid chromatography

Abstract

The ionogel material has functional designability and a network structure, so we designed this new ionogel@silica composite material that can be used as a stationary phase in liquid chromatography. 1-Allyl-3-vinylimidazolium tetrafluoroborate was bonded and chemically cross-linked on the surface of silica microspheres through the thiol olefin click reaction. Dodecanethiol was used as the end-capping group to prepare this new type of stationary phase. Infrared spectroscopy, elemental analysis, scanning electron microscopy, thermogravimetric analysis and other methods were used to demonstrate the successful preparation of this material. It can overcome the limited retention problem of purely hydrophilic group-modified chromatographic columns. Analytes such as nucleosides/bases, amino acids, sulfanilamides, polycyclic aromatic hydrocarbons and complex samples were separated and tested on ion gel-bonded chromatographic columns. The results show that the preparation of this new type of gel-bonded chromatographic column expands the possibility of applying gel materials in liquid chromatographic separation. This method provides a general method for easily incorporating various functional groups into chromatographic materials to develop stimulus-responsive liquid chromatography.