Issue 11, 2021

Facile synthesis of nitrogen-doped carbon dots from pork liver and its sensing of 6-thioguanine based on the inner filter effect

Abstract

In this work, a facile one-step hydrothermal method was developed to synthesize nitrogen-doped carbon dots (N-CDs) using pork liver. The quantum yield of the prepared N-CDs was as high as 11.74%. The excitation and emission wavelengths of the N-CDs were 329 and 410 nm, respectively. The excitation spectrum of the N-CDs has a big overlap with the absorption band of 6-thioguanine (6-TG), which formed an inner filter effect (IFE) between them. 6-TG acted as an effective absorber in IFE to quench the fluorescence of the N-CDs. The concentration of 6-TG was well linear with the fluorescence quenching intensity of the system from 1 μM to 200 μM. The limit of detection was as low as 0.75 μM. This proposed method was successfully applied in selective and sensitive determination of 6-TG in human serum with recoveries of 96.2–105.3%.

Graphical abstract: Facile synthesis of nitrogen-doped carbon dots from pork liver and its sensing of 6-thioguanine based on the inner filter effect

Supplementary files

Article information

Article type
Paper
Submitted
11 Nov 2020
Accepted
19 Feb 2021
First published
19 Feb 2021

New J. Chem., 2021,45, 5114-5120

Facile synthesis of nitrogen-doped carbon dots from pork liver and its sensing of 6-thioguanine based on the inner filter effect

W. Chen, J. Fan, X. Wu, D. Hu, Y. Wu, Z. Feng, M. Yan, X. Gao and J. Xie, New J. Chem., 2021, 45, 5114 DOI: 10.1039/D0NJ05483F

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