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A thermoresponsive crosslinker for reversible micelle stabilization

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Abstract

Herein we report a thermoresponsive crosslinker that can be utilized to stabilize the surface of micelles through a “click” reaction and to trigger the disassembly via a retro Diels Alder (rDA) mechanism. The micelles generated were 100 nm in size and monodispersed. Above 60 °C, rDA dissociation of crosslinker occurs resulting to the degradation of the micelles and release of hydrophobic cargo.

Graphical abstract: A thermoresponsive crosslinker for reversible micelle stabilization

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Article information


Submitted
30 Jan 2021
Accepted
09 Mar 2021
First published
16 Mar 2021

This article is Open Access

Mater. Adv., 2021, Advance Article
Article type
Communication

A thermoresponsive crosslinker for reversible micelle stabilization

M. Q. Tolentino and J. L. Rouge, Mater. Adv., 2021, Advance Article , DOI: 10.1039/D1MA00089F

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