Issue 7, 2021

A thermoresponsive crosslinker for reversible micelle stabilization

Abstract

Herein we report a thermoresponsive crosslinker that can be utilized to stabilize the surface of micelles through a “click” reaction and to trigger the disassembly via a retro Diels Alder (rDA) mechanism. The micelles generated were 100 nm in size and monodispersed. Above 60 °C, rDA dissociation of crosslinker occurs resulting to the degradation of the micelles and release of hydrophobic cargo.

Graphical abstract: A thermoresponsive crosslinker for reversible micelle stabilization

Supplementary files

Article information

Article type
Communication
Submitted
30 Jan 2021
Accepted
09 Mar 2021
First published
16 Mar 2021
This article is Open Access
Creative Commons BY-NC license

Mater. Adv., 2021,2, 2267-2271

A thermoresponsive crosslinker for reversible micelle stabilization

M. Q. Tolentino and J. L. Rouge, Mater. Adv., 2021, 2, 2267 DOI: 10.1039/D1MA00089F

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