Electrochemical-mediated fixation of CO2: three-component synthesis of carbamate compounds from CO2, amines and N-alkenylsulfonamides

Abstract

An electrocatalyzed three-component cascade reaction of CO₂, amines, and N-alkenylsulfonamides is developed, providing an environmentally friendly and efficient method of synthesizing a series of new carbamate compounds. This reaction meets the needs of green chemistry and promotes the participation of carbon dioxide in the three-component reaction by electro-oxidation. Pharmacological activity studies further prove that carbamate compounds have better activity than diamination by-products.