Boron carbonitride photocatalysts for direct decarboxylation: the construction of C(sp3)–N or C(sp3)–C(sp2) bonds with visible light

Abstract

A metal-free protocol is established for the decarboxylative N–H or C(sp²)–H functionalization of acids via metal-free boron carbon nitride (BCN) photocatalysis, delivering the desired products under ambient conditions. This methodology is applicable to the late-stage modification of pharmaceutical molecules and gram-scale experiments as well as in the recovery and reuse of the photocatalysts without the loss of reactivity. The developed photochemical reaction system fulfills the requirements of green and sustainable chemistry.