Separation of a diastereomeric diol pair using mechanical properties of crystals

Abstract

We report the separation of visually indistinguishable acicular morphologies of (2S,3R/S)-3-ethyl-1-phenylhex-5-ene-2,3-diol (ephd) diastereomeric pair based on their mechanical responses, which is found to be more efficient than conventional separation methods. Furthermore, the molecular crystals of (2S,3R)-ephd show elastic deformation, while (2S,3S)-ephd fracture in a brittle manner under similar conditions.

Article information

Article type
Communication
Submitted
09 Aug 2021
Accepted
14 Sep 2021
First published
15 Sep 2021

CrystEngComm, 2021, Accepted Manuscript

Separation of a diastereomeric diol pair using mechanical properties of crystals

R. K. Gamidi, M. Dandawate, R. Choudhury, S. Tothadi, A. Nangia and D. S. Reddy, CrystEngComm, 2021, Accepted Manuscript , DOI: 10.1039/D1CE01055G

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements