Issue 69, 2021

Activatable photoacoustic/fluorescent dual-modal probe for monitoring of drug-induced liver hypoxia in vivo

Abstract

Effective monitoring of liver hypoxia status is crucial for the detection and treatment of drug-induced liver injury. Here, a novel photoacoustic and fluorescent dual-modal probe (NO2-CS) was rationally developed and applied to image isoniazid-induced liver hypoxia through detecting the over-expressed nitroreductase.

Graphical abstract: Activatable photoacoustic/fluorescent dual-modal probe for monitoring of drug-induced liver hypoxia in vivo

Supplementary files

Article information

Article type
Communication
Submitted
07 Jun 2021
Accepted
27 Jul 2021
First published
27 Jul 2021

Chem. Commun., 2021,57, 8644-8647

Activatable photoacoustic/fluorescent dual-modal probe for monitoring of drug-induced liver hypoxia in vivo

X. Fan, T. Ren, W. Yang, X. Zhang and L. Yuan, Chem. Commun., 2021, 57, 8644 DOI: 10.1039/D1CC02999A

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