Issue 63, 2021

A turn-on probe for detecting antituberculotic drug-induced liver injury in mice via NIR-II fluorescence/optoacoustic imaging

Abstract

A turn-on optoacoustic and NIR-II fluorescent probe for imaging antituberculotic drug-induced liver injury has been developed. Probe TC-H2O2 responds to hepatic H2O2, thus releasing chromophore TC-NN, which displays prominent NIR-II fluorescence and optoacoustic signals for diagnosing liver injury.

Graphical abstract: A turn-on probe for detecting antituberculotic drug-induced liver injury in mice via NIR-II fluorescence/optoacoustic imaging

Supplementary files

Article information

Article type
Communication
Submitted
29 May 2021
Accepted
12 Jul 2021
First published
12 Jul 2021

Chem. Commun., 2021,57, 7842-7845

A turn-on probe for detecting antituberculotic drug-induced liver injury in mice via NIR-II fluorescence/optoacoustic imaging

L. Chen, J. Chen, Y. Fang, F. Zeng and S. Wu, Chem. Commun., 2021, 57, 7842 DOI: 10.1039/D1CC02845F

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