Straightforward N-alkylation of diketopyrrolopyrroles through the Mitsunobu reaction with benzyl, α-branched, and chiral alcohols

Abstract

The N-alkylation of diketopyrrolopyrroles (DPPs) represents a fundamental step to ensure solubility and further processability. Commonly used nucleophilic substitution in halogenated derivatives is replaced in this work by the Mitsunobu reaction affording unprecedented DPPs with α-branched and chiral chains.