Issue 56, 2021
From the journal:

Chemical Communications

Highly selective two-photon fluorescent off–on probes for imaging tyrosinase activity in living cells and tissues†

Yixin Cui,‡a   Sang Jun Park,‡b   Xiaofeng Wu,*a   Rui Wang,a   Sujie Qi, ORCID logo a   Hwan Myung Kim ORCID logo *b  and  Juyoung Yoon ORCID logo *a  

* Corresponding authors

a Department of Chemistry and Nanoscience, Ewha Womans University, Seoul, Korea
E-mail: jyoon@ewha.ac.kr

b Department of Chemistry and Department of Energy Systems Research, Ajou University, Suwon, Korea
E-mail: kimhm@ajou.ac.kr

Abstract

A coumarin-based two-photon (TP) fluorescent off–on probe has been developed for detecting tyrosinase activity. High selectivity, sensitivity and biocompatibility enable the probes to successfully image tyrosinase activity in live cells and tissues using TP microscopy.

Graphical abstract: Highly selective two-photon fluorescent off–on probes for imaging tyrosinase activity in living cells and tissues

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Article information

DOI
https://doi.org/10.1039/D1CC02374H
Article type
Communication
Submitted
05 May 2021
Accepted
14 Jun 2021
First published
14 Jun 2021

Chem. Commun., 2021,57, 6911-6914

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Highly selective two-photon fluorescent off–on probes for imaging tyrosinase activity in living cells and tissues

Y. Cui, S. J. Park, X. Wu, R. Wang, S. Qi, H. M. Kim and J. Yoon, Chem. Commun., 2021, 57, 6911 DOI: 10.1039/D1CC02374H

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