Positively charged collective oscillations induce efficient Aβ1–42 fibril degradation in the presence of novel Au@Cu2−xS core/shell nanorods

Xiaodong Wan; Meng Xu; Liu Huang; Guopeng Tu; Muwei Ji; Mengyao Su; Yuemei Li; Xinyuan Li; Hongzhi Wang; Jiatao Zhang

doi:10.1039/D1CC01470F

Positively charged collective oscillations induce efficient Aβ1–42 fibril degradation in the presence of novel Au@Cu_2−xS core/shell nanorods†

Xiaodong Wan,^a Meng Xu,*^ab Liu Huang,^a Guopeng Tu,^a Muwei Ji,

^a Mengyao Su,^a Yuemei Li,^a Xinyuan Li,^a Hongzhi Wang^a and Jiatao Zhang

*^ab

Author affiliations

* Corresponding authors

^a Beijing Key Laboratory of Construction Tailorable Advanced Functional Materials and Green Applications, Experimental Center of Advanced Materials, School of Materials Science and Engineering, Beijing Institute of Technology, China
E-mail: xumeng@bit.edu.cn, zhangjt@bit.edu.cn

^b Key Laboratory of Medical Molecular Science and Pharmaceutical Engineering, MIIT, Institute for Engineering Medicine, BIT, Beijing 100081, China

Abstract

We synthesized Au@Cu_2−xS core/shell nanorods (NRs) that have synergistic surface plasmon resonance (SPR) effects using a new cation exchange process in ethylene glycol (EG) phase. The dual effect – NIR photothermal and surface positive charge plasmon – of Au@Cu_2−xS NRs, promote the capability to degrade Aβ1–42 fibrils into amorphous protein.

Chemical Communications

Positively charged collective oscillations induce efficient Aβ1–42 fibril degradation in the presence of novel Au@Cu_2−xS core/shell nanorods†

Abstract

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Positively charged collective oscillations induce efficient Aβ1–42 fibril degradation in the presence of novel Au@Cu_2−xS core/shell nanorods

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Chemical Communications

Positively charged collective oscillations induce efficient Aβ1–42 fibril degradation in the presence of novel Au@Cu2−xS core/shell nanorods†

Abstract

Supplementary files

Article information

Download Citation

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Positively charged collective oscillations induce efficient Aβ1–42 fibril degradation in the presence of novel Au@Cu2−xS core/shell nanorods

Social activity

Search articles by author

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Positively charged collective oscillations induce efficient Aβ1–42 fibril degradation in the presence of novel Au@Cu_2−xS core/shell nanorods†

Positively charged collective oscillations induce efficient Aβ1–42 fibril degradation in the presence of novel Au@Cu_2−xS core/shell nanorods