Issue 44, 2021

AES and ToF-SIMS combination for single cell chemical imaging of gold nanoparticle-labeled Escherichia coli

Abstract

A chemical fingerprint of the Escherichia coli cell surface labeled by gelatin coated gold nanoparticles was obtained by combining Auger Electron Spectroscopy (AES) for single cell level chemical images, and Time-of-Flight Secondary Ion Mass Spectroscopy (ToF-SIMS) Tandem MS for unambiguous molecular identification of co-localized species.

Graphical abstract: AES and ToF-SIMS combination for single cell chemical imaging of gold nanoparticle-labeled Escherichia coli

Supplementary files

Article information

Article type
Communication
Submitted
05 Mar 2021
Accepted
27 Apr 2021
First published
27 Apr 2021

Chem. Commun., 2021,57, 5446-5449

AES and ToF-SIMS combination for single cell chemical imaging of gold nanoparticle-labeled Escherichia coli

C. Courrèges, M. Bonnecaze, D. Flahaut, S. Nolivos, R. Grimaud and J. Allouche, Chem. Commun., 2021, 57, 5446 DOI: 10.1039/D1CC01211H

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