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In vivo monitoring of volatile metabolic trajectories enables rapid diagnosis of influenza A infection

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Abstract

We report that influenza A virus infection induces changes in odor traits that could be captured by real-time high-resolution mass spectrometry in a living mouse model. The most striking changes in the volatile metabolites may be associated mostly to glyoxylate/dicarboxylate metabolism.

Graphical abstract: In vivo monitoring of volatile metabolic trajectories enables rapid diagnosis of influenza A infection

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Article information


Submitted
25 Feb 2021
Accepted
07 Apr 2021
First published
07 Apr 2021

Chem. Commun., 2021, Advance Article
Article type
Communication

In vivo monitoring of volatile metabolic trajectories enables rapid diagnosis of influenza A infection

Z. Yin, W. Huang, K. D. Singh, Z. Chen, X. Chen, Z. Zhou, Z. Yang, P. Sinues and X. Li, Chem. Commun., 2021, Advance Article , DOI: 10.1039/D1CC01061A

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