Issue 31, 2021

Clues from cocrystals: a ternary solid, polymorphism, and rare supramolecular isomerism involving resveratrol and 5-fluorouracil

Abstract

We describe a supramolecular synthesis of a ternary cocrystal involving resveratrol and 5-fluorouracil (5-fu) with trans-bis(4-pyridyl)ethylene (bpe). We also have discovered a polymorph of a binary cocrystal involving 5-fu and bpe that originates from rare supramolecular isomerism.

Graphical abstract: Clues from cocrystals: a ternary solid, polymorphism, and rare supramolecular isomerism involving resveratrol and 5-fluorouracil

Supplementary files

Article information

Article type
Communication
Submitted
28 Dec 2020
Accepted
09 Mar 2021
First published
10 Mar 2021

Chem. Commun., 2021,57, 3809-3811

Author version available

Clues from cocrystals: a ternary solid, polymorphism, and rare supramolecular isomerism involving resveratrol and 5-fluorouracil

C. Ortiz-de León and L. R. MacGillivray, Chem. Commun., 2021, 57, 3809 DOI: 10.1039/D0CC08388G

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