Selective transmembrane transport of Aβ protein regulated by tryptophan enantiomers

Abstract

Tryptophan enantiomers (D/L-Trp) were introduced into artificial nanochannels to regulate the chiral selective transport of Aβ proteins. The L-Trp channel performs effectively selectivity for the transport of Aβ protein, which would provide a new perspective for the pathological studies of Alzheimer's disease.