Issue 8, 2021

The role of poly(2-alkyl-2-oxazoline)s in hydrogels and biofabrication

Abstract

Poly(2-alkyl-2-oxazoline)s (PAOXAs) have been rapidly emerging as starting materials in the design of tissue engineering supports and for the generation of platforms for cell cultures, especially in the form of hydrogels. Thanks to their biocompatibility, chemical versatility and robustness, PAOXAs now represent a valid alternative to poly(ethylene glycol)s (PEGs) and their derivatives in these applications, and in the formulation of bioinks for three-dimensional (3D) bioprinting. In this review, we summarize the recent literature where PAOXAs have been used as main components for hydrogels and biofabrication mixtures, especially highlighting how their easily tunable composition could be exploited to fabricate multifunctional biomaterials with an extremely broad spectrum of properties.

Graphical abstract: The role of poly(2-alkyl-2-oxazoline)s in hydrogels and biofabrication

Article information

Article type
Minireview
Submitted
30 Dec 2020
Accepted
16 Feb 2021
First published
22 Feb 2021
This article is Open Access
Creative Commons BY-NC license

Biomater. Sci., 2021,9, 2874-2886

The role of poly(2-alkyl-2-oxazoline)s in hydrogels and biofabrication

L. Trachsel, M. Zenobi-Wong and E. M. Benetti, Biomater. Sci., 2021, 9, 2874 DOI: 10.1039/D0BM02217A

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