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Issue 18, 2021
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Exploring the utility of Au@PVP-polyamide-Triton X-114 for SERS tracking of extracellular senescence associated-beta-galactosidase activity

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Abstract

A compound with enrichment and SERS enhancement was successfully developed, which could rapidly adsorb X-gal hydrolysates from a liquid matrix in 5 minutes and further be used for SERS analysis with a detection limit of less than 1 × 10−9 mol L−1. This novel strategy will facilitate the development of an analytical approach for cellular senescence.

Graphical abstract: Exploring the utility of Au@PVP-polyamide-Triton X-114 for SERS tracking of extracellular senescence associated-beta-galactosidase activity

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Article information


Submitted
19 Mar 2021
Accepted
14 Apr 2021
First published
14 Apr 2021

Anal. Methods, 2021,13, 2087-2091
Article type
Communication

Exploring the utility of Au@PVP-polyamide-Triton X-114 for SERS tracking of extracellular senescence associated-beta-galactosidase activity

S. Li, Y. Cheng, M. Qin, S. Chen, P. Li and L. Yang, Anal. Methods, 2021, 13, 2087
DOI: 10.1039/D1AY00470K

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