Jump to main content
Jump to site search

Issue 16, 2021
Previous Article Next Article

A novel fluorescence probe for the selective detection of cysteine in aqueous solutions and imaging in living cells and mice

Author affiliations

Abstract

A novel fluorescent probe based on hydroxyquinoline conjugated with a charged trimethylindolenine unit Toc-Ac was developed, which exhibited long wavelength emission (560 nm) and a large Stokes shift (∼140 nm) due to the intrinsic mechanism of the intramolecular charge transfer process. The probe Toc-Ac showed a highly sensitive response to Cys (the detection limit was 3.86 × 10−8 M) in aqueous solution and was successfully applied for detecting endogenous Cys in living cells and mice.

Graphical abstract: A novel fluorescence probe for the selective detection of cysteine in aqueous solutions and imaging in living cells and mice

Back to tab navigation

Supplementary files

Article information


Submitted
01 Feb 2021
Accepted
16 Mar 2021
First published
17 Mar 2021

Anal. Methods, 2021,13, 1965-1969
Article type
Paper

A novel fluorescence probe for the selective detection of cysteine in aqueous solutions and imaging in living cells and mice

H. Mei, D. Wang, M. Wang, X. Gu, X. Liu and L. Yang, Anal. Methods, 2021, 13, 1965
DOI: 10.1039/D1AY00178G

Social activity

Search articles by author

Spotlight

Advertisements