Selective colorimetric sensing of sub-nanomolar Hg2+ based on its significantly enhancing peroxidase mimics of silver/copper nanoclusters

Abstract

A simple colorimetric sensing strategy for Hg²⁺ ions was developed using silver/copper nanoclusters (Ag/Cu NCs) with excellent selectivity and sensitivity. Bimetallic Ag/Cu NCs were synthesized by using glutathione (GSH) as a template and sodium borohydride as a reducing agent. It was found that the peroxidase-like activity of Ag/Cu NCs was significantly enhanced in the presence of Hg²⁺. Therefore, a colorimetric method based on catalysis was developed to detect Hg²⁺ with a linear concentration range of 0.1–700 nM and a detection limit of 0.05 nM (S/N = 3). The common species have no effect on Hg²⁺ ion detection. Furthermore, this method is applicable to accurately detect Hg²⁺ in real aqueous samples and is reproducible. Therefore, owing to the merits of sensitivity, selectivity, rapid response and visual read-out, it can be promising in the development of a portable Hg²⁺ analyzer for on-site detection.