Jump to main content
Jump to site search

Issue 7, 2021
Previous Article Next Article

Development of a piperazinyl-NBD-based fluorescent probe and its dual-channel detection for hydrogen sulfide

Author affiliations

Abstract

To selectively detect H2S based on the thiolysis reaction of 7-nitro-1,2,3-benzoxadiazole (NBD), amines attracted increasing attention since NBD amine is regarded as a new H2S reaction site. Herein, a novel fluorescent probe, triphenylamine piperazine NBD (TPA-Pz-NBD), was developed. The results showed that it exhibited high selectivity towards H2S via fluorescence spectroscopy and solution color. Furthermore, TPA-Pz-NBD not only detected H2S by a dual-channel, turn-on fluorescence signal at 500 nm and turn-off fluorescence signal at 545 nm, respectively, but also displayed a wide detection range of 0–125 μM. In addition, living cell imaging results indicated that TPA-Pz-NBD holds potential for the detection of intracellular H2S.

Graphical abstract: Development of a piperazinyl-NBD-based fluorescent probe and its dual-channel detection for hydrogen sulfide

Back to tab navigation

Supplementary files

Article information


Submitted
11 Jan 2021
Accepted
17 Feb 2021
First published
17 Feb 2021

Analyst, 2021,146, 2138-2143
Article type
Paper

Development of a piperazinyl-NBD-based fluorescent probe and its dual-channel detection for hydrogen sulfide

S. Pei, J. Li, C. Zhang, W. Liang, G. Zhang, L. Shi, W. Wang, S. Shuang and C. Dong, Analyst, 2021, 146, 2138
DOI: 10.1039/D1AN00054C

Social activity

Search articles by author

Spotlight

Advertisements