Issue 6, 2021
From the journal:

Analyst

A ratiometric electrochemiluminescent cytosensor based on polyaniline hydrogel electrodes in spatially separated electrochemiluminescent systems†

Gen Liu, ORCID logo abc   Zixuan Chen, ORCID logo a   Bao-Kang Jinc  and  Li-Ping Jiang ORCID logo *a  

* Corresponding authors

a State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, China
E-mail: jianglp@nju.edu.cn

b College of Chemistry and Material Science, Huaibei Normal University, Huaibei, China

c College of Chemistry & Chemical Engineering, Anhui University, Hefei, China

Abstract

Here, we proposed a ratiometric electrochemiluminescent (ECL) strategy in spatially multiplied ECL systems. By the specific recognition of hyaluronic acid with proteoglycan CD44 and epidermal growth factor with epidermal growth factor receptor on the cell surface, the cells were labelled with potential-resolved ECL probes, namely Ru(bpy)32+ and g-C3N4, respectively. The as-proposed cytosensor provides a multichannel ECL protocol to improve the throughput, which may push the application of ECL for the cellular immunoanalysis.

Graphical abstract: A ratiometric electrochemiluminescent cytosensor based on polyaniline hydrogel electrodes in spatially separated electrochemiluminescent systems

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Article information

DOI
https://doi.org/10.1039/D0AN02408B
Article type
Communication
Submitted
17 Dec 2020
Accepted
14 Jan 2021
First published
15 Jan 2021

Analyst, 2021,146, 1835-1838

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A ratiometric electrochemiluminescent cytosensor based on polyaniline hydrogel electrodes in spatially separated electrochemiluminescent systems

G. Liu, Z. Chen, B. Jin and L. Jiang, Analyst, 2021, 146, 1835 DOI: 10.1039/D0AN02408B

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