L-Cysteine/AgNO2 low molecular weight gelators: self-assembly and suppression of MCF-7 breast cancer cells

Dmitry V. Vishnevetskii; Arif R. Mekhtiev; Tatyana V. Perevozova; Dmitry V. Averkin; Alexandra I. Ivanova; Svetlana D. Khizhnyak; Pavel M. Pakhomov

doi:10.1039/D0SM01431A

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l-Cysteine/AgNO₂ low molecular weight gelators: self-assembly and suppression of MCF-7 breast cancer cells†

Dmitry V. Vishnevetskii,

*^a Arif R. Mekhtiev,*^b Tatyana V. Perevozova,^a Dmitry V. Averkin,^a Alexandra I. Ivanova,^a Svetlana D. Khizhnyak^a and Pavel M. Pakhomov^a

Author affiliations

* Corresponding authors

^a Department of Physical Chemistry and Applied Physics, Tver State University, Tver, Russia
E-mail: rickashet@yandex.ru

^b Institute of Biomedical Chemistry (IBMC), Moscow, Russia
E-mail: marif@yandex.ru

Abstract

We report a new supramolecular hydrogel based on simple amino acids and silver salt compounds with low molecular weights. The in situ formation of silver nanoparticles during the self-assembly process endows the hydrogel with high cytotoxicity towards adenocarcinoma breast cells but no toxic effects towards embryonic fibroblasts.

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Article information

DOI: https://doi.org/10.1039/D0SM01431A
Article type: Communication
Submitted: 05 Aug 2020
Accepted: 03 Oct 2020
First published: 05 Oct 2020

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Soft Matter, 2020,16, 9669-9673

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L-Cysteine/AgNO₂ low molecular weight gelators: self-assembly and suppression of MCF-7 breast cancer cells

D. V. Vishnevetskii, A. R. Mekhtiev, T. V. Perevozova, D. V. Averkin, A. I. Ivanova, S. D. Khizhnyak and P. M. Pakhomov, Soft Matter, 2020, 16, 9669 DOI: 10.1039/D0SM01431A

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