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Issue 39, 2020
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Fluid–fluid coexistence in phospholipid membranes induced by decanol

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Abstract

We have observed fluid–fluid coexistence in 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) membrane containing 1-decanol, using different experimental techniques and membrane morphologies. This phase behavior is reversible and occurs over a temperature range just above the chain melting transition temperature of the membrane. Although earlier experimental studies and computer simulations have shown the ability of decanol to enhance lipid chain ordering, its potential to induce fluid–fluid coexistence in membranes has not been hitherto recognized. Being the only binary membrane system known so far to exhibit fluid–fluid coexistence, the present system can serve as a simple model to gain a better understanding of mechanisms that drive this unusual phase behavior, which is believed to play an important role in the functioning of cell membranes.

Graphical abstract: Fluid–fluid coexistence in phospholipid membranes induced by decanol

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Article information


Submitted
03 Aug 2020
Accepted
21 Sep 2020
First published
21 Sep 2020

Soft Matter, 2020,16, 9002-9005
Article type
Communication

Fluid–fluid coexistence in phospholipid membranes induced by decanol

B. Suryabrahmam, A. Agrawal and V. A. Raghunathan, Soft Matter, 2020, 16, 9002
DOI: 10.1039/D0SM01417F

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