Issue 64, 2020

A facile metal-free one-pot synthesis of 3-aminoisoquinolines by intramolecular transannulation of 1-sulfonyl-4-(2-aminomethylphenyl)-1,2,3-triazoles

Abstract

A metal-free one-pot intramolecular transannulation of 1-sulfonyl-4-(2-aminomethylphenyl)-1,2,3-triazoles has been developed, which enables the facile synthesis of the various 3-aminoisoquinolines as well as relevant scaffolds from readily available starting materials.

Graphical abstract: A facile metal-free one-pot synthesis of 3-aminoisoquinolines by intramolecular transannulation of 1-sulfonyl-4-(2-aminomethylphenyl)-1,2,3-triazoles

Supplementary files

Article information

Article type
Paper
Submitted
29 Jul 2020
Accepted
06 Sep 2020
First published
28 Oct 2020
This article is Open Access
Creative Commons BY-NC license

RSC Adv., 2020,10, 39067-39071

A facile metal-free one-pot synthesis of 3-aminoisoquinolines by intramolecular transannulation of 1-sulfonyl-4-(2-aminomethylphenyl)-1,2,3-triazoles

H. Shang, L. Li, Y. Tian, H. Jia and Z. Zou, RSC Adv., 2020, 10, 39067 DOI: 10.1039/D0RA06563C

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