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Issue 51, 2020
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Mannich bases derived from lawsone and their metal complexes: synthetic strategies and biological properties

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Abstract

Lawsone (2-hydroxynaphthalene-1,4-dione) is a natural product which shows significant biological activity. Aminomethylnaphthoquinone Mannich bases derived from lawsone constitute an interesting class of naphthoquinones and/or their metal complexes have demonstrated a series of important biological properties. So, this review aimed to document the publications concerning the synthesis of aminomethylnaphthoquinone Mannich bases from lowsone, aldehydes and amines and their metal complexes using different conditions, and investigation of their applications.

Graphical abstract: Mannich bases derived from lawsone and their metal complexes: synthetic strategies and biological properties

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Article information


Submitted
30 Jun 2020
Accepted
30 Jul 2020
First published
17 Aug 2020

This article is Open Access

RSC Adv., 2020,10, 30265-30281
Article type
Review Article

Mannich bases derived from lawsone and their metal complexes: synthetic strategies and biological properties

A. Olyaei, M. Sadeghpour and M. Khalaj, RSC Adv., 2020, 10, 30265
DOI: 10.1039/D0RA05717G

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. Material from this article can be used in other publications provided that the correct acknowledgement is given with the reproduced material.

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    [Original citation] - Published by The Royal Society of Chemistry (RSC) on behalf of the Centre National de la Recherche Scientifique (CNRS) and the RSC.
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    [Original citation] - Published by The Royal Society of Chemistry (RSC) on behalf of the European Society for Photobiology, the European Photochemistry Association, and RSC.
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    [Original citation] - Published by The Royal Society of Chemistry.

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