Issue 37, 2020

Nickel catalyzed intramolecular oxidative coupling: synthesis of 3-aryl benzofurans

Abstract

Recent research has been focused on the transition metal-catalyzed reactions. Herein we have developed nickel-catalyzed synthesis of 3-aryl benzofurans from ortho-alkenyl phenols via intramolecular dehydrogenative coupling. Notably, simple O2 gas served as an oxidant, without using any sacrificial hydrogen acceptor. The strategy enabled the synthesis of 3-aryl benzofurans in good to excellent yields.

Graphical abstract: Nickel catalyzed intramolecular oxidative coupling: synthesis of 3-aryl benzofurans

Supplementary files

Article information

Article type
Paper
Submitted
05 Apr 2020
Accepted
27 May 2020
First published
10 Jun 2020
This article is Open Access
Creative Commons BY-NC license

RSC Adv., 2020,10, 22264-22272

Nickel catalyzed intramolecular oxidative coupling: synthesis of 3-aryl benzofurans

S. Aggarwal, D. Srinivas, C. Sreenivasulu and G. Satyanarayana, RSC Adv., 2020, 10, 22264 DOI: 10.1039/D0RA03071F

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