Issue 11, 2020, Issue in Progress

Photostable near-infrared-absorbing diradical-platinum(ii) complex solubilized by albumin toward a cancer photothermal therapy agent

Abstract

A hydrophobic diradical-platinum(II) complex was solubilized in aqueous solutions by using bovine serum albumin and exhibited photothermal conversion under near-infrared (NIR) light irradiation. The complex was introduced into cancer cells and induced cell death upon absorption of NIR. These results imply that the complex can function as a photothermal therapeutic agent.

Graphical abstract: Photostable near-infrared-absorbing diradical-platinum(ii) complex solubilized by albumin toward a cancer photothermal therapy agent

Supplementary files

Article information

Article type
Paper
Submitted
11 Dec 2019
Accepted
03 Feb 2020
First published
11 Feb 2020
This article is Open Access
Creative Commons BY-NC license

RSC Adv., 2020,10, 6460-6463

Photostable near-infrared-absorbing diradical-platinum(II) complex solubilized by albumin toward a cancer photothermal therapy agent

R. Sawamura, M. Sato, A. Masuya-Suzuki and N. Iki, RSC Adv., 2020, 10, 6460 DOI: 10.1039/D0RA00652A

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