Issue 8, 2020

Rhodium-catalyzed asymmetric transfer hydrogenation of 4-quinolone derivatives

Abstract

4-Quinolone derivatives were conveniently reduced to the corresponding 1,2,3,4-tetrahydroquinoline-4-ols with excellent enantioselectivities through asymmetric transfer hydrogenation using a tethered rhodium complex and formic acid/triethylamine as the hydride source.

Graphical abstract: Rhodium-catalyzed asymmetric transfer hydrogenation of 4-quinolone derivatives

Supplementary files

Article information

Article type
Research Article
Submitted
20 Dec 2019
Accepted
24 Jan 2020
First published
05 Feb 2020

Org. Chem. Front., 2020,7, 975-979

Rhodium-catalyzed asymmetric transfer hydrogenation of 4-quinolone derivatives

B. He, P. Phansavath and V. Ratovelomanana-Vidal, Org. Chem. Front., 2020, 7, 975 DOI: 10.1039/C9QO01514K

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