Issue 16, 2020

Mussel-inspired coordination functional polymer brushes-decorated rGO-stabilized silver nanoparticles composite for antibacterial application

Abstract

Functionalized GO nanosheets and their nanohybrids are demonstrated to have promising biomedical applications. In this article, we design and prepare a novel catechol-terminated copolymer (CCP) containing poly(ethylene glycol) methyl ether methacrylate (PEGMA) and 2,3-epithiopropyl methacrylate (ETMA) segments via reversible addition–fragmentation chain transfer radical polymerization. The coordination functional CCP can be easily attached to the surface of reduced graphene oxide (rGO) through mussel-inspired chemistry under mild conditions. The obtained two-dimensional CCP-rGO nanosheets are utilized as a platform to construct a CCP-rGO supported well-dispersed Ag nanoparticles composite (CCP-rGO-Ag) through in situ reduction. The as-prepared CCP-rGO-Ag nanocomposite has powerful and long-lasting antibacterial activity against G (E. coli) and G+ (S. epidermidis and S. aureus). Compared with rGO-Ag without polymer modification, CCP-rGO-Ag has lower cytotoxicity and excellent performance due to the introduction of a hydrophilic coordination polymer. Overall, our study reveals a novel method of preparing copolymer brushes-modified rGO-based antibacterial nanomaterials and provides a feasible strategy to fight bacterial resistance threats to human health.

Graphical abstract: Mussel-inspired coordination functional polymer brushes-decorated rGO-stabilized silver nanoparticles composite for antibacterial application

Supplementary files

Article information

Article type
Paper
Submitted
03 Feb 2020
Accepted
14 Mar 2020
First published
19 Mar 2020

Polym. Chem., 2020,11, 2822-2830

Mussel-inspired coordination functional polymer brushes-decorated rGO-stabilized silver nanoparticles composite for antibacterial application

S. Zhou, H. Ji, L. Liu, S. Feng, Y. Fu, Y. Yang and C. Lü, Polym. Chem., 2020, 11, 2822 DOI: 10.1039/D0PY00180E

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