Issue 43, 2020

Synthesis of Au/Bi2S3 nanoflowers for efficient photothermal therapy

Abstract

A therapeutic nanoplatform with effective photothermal cancer treatment attracts enormous attention but still faces great challenges, such as a tedious preparation process, poor biocompatibility and low efficiency. In this study, we prepared Au/Bi2S3 nanoflowers (NFs) as high-performance cancer photothermal agents for the first time. This was achieved in a facile and mild way by using bovine serum albumin (BSA) as reducer and stabilizer. In this process, Bi3+ and Au3+ underwent in situ reduction and growth, and then formed flower-like Au/Bi2S3 nanocomposites. The results revealed that the as-prepared Au/Bi2S3 NFs with special morphology showed high stability, excellent biocompatibility and good photostability. Apart from these, it was also observed that the Au/Bi2S3 NFs can efficiently convert the near-infrared (NIR) light into heat leading to high performance in photothermal conversion efficiency (up to 58.34%), and then suppressed the growth of tumor cells under NIR laser irradiation. This work highlights the potential of Au/Bi2S3 NFs as photothermal agents for cancer ablation treatment in the future.

Graphical abstract: Synthesis of Au/Bi2S3 nanoflowers for efficient photothermal therapy

Supplementary files

Article information

Article type
Paper
Submitted
27 Aug 2020
Accepted
06 Oct 2020
First published
08 Oct 2020

New J. Chem., 2020,44, 18724-18731

Synthesis of Au/Bi2S3 nanoflowers for efficient photothermal therapy

X. Zhao, S. Li, T. Huang, H. Sun, H. Zhu, H. Guo and M. Liu, New J. Chem., 2020, 44, 18724 DOI: 10.1039/D0NJ04313C

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