Issue 38, 2020
From the journal:

New Journal of Chemistry

An HBT-based fluorescent probe for nitroreductase determination and its application in Escherichia coli cell imaging†

Quanzhi Yang,ab   Yujie Wen,ab   Aiguo Zhong,c   Jian Xua  and  Shijun Shao ORCID logo *a  

* Corresponding authors

a CAS Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou, Gansu 730000, P. R. China
E-mail: sjshao@licp.cas.cn

b University of Chinese Academy of Sciences, Beijing 100049, P. R. China

c Department of Chemistry, Taizhou College, Taizhou 318000, P. R. China

Abstract

A novel HBT-based fluorescent probe HBTPN was reasonably designed for detecting nitroreductase by merging 4-nitrobenzyl as a sensing moiety to HBT-based dye HBTPP. Experiments showed that probe HBTPN displayed a selective and sensitive “turn-on” response towards nitroreductase and has been applied for sensing nitroreductase in live Escherichia coli.

Graphical abstract: An HBT-based fluorescent probe for nitroreductase determination and its application in Escherichia coli cell imaging

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Supplementary files

Article information

DOI
https://doi.org/10.1039/D0NJ03286G
Article type
Letter
Submitted
30 Jun 2020
Accepted
28 Aug 2020
First published
01 Sep 2020

New J. Chem., 2020,44, 16265-16268

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An HBT-based fluorescent probe for nitroreductase determination and its application in Escherichia coli cell imaging

Q. Yang, Y. Wen, A. Zhong, J. Xu and S. Shao, New J. Chem., 2020, 44, 16265 DOI: 10.1039/D0NJ03286G

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