Issue 30, 2020

Structural divergence in binuclear Cu(ii) pyridoxal Schiff base complexes probed by co-ligands: catecholase mimetic activity and sulphide ion sensing

Abstract

Three hydroxymethyl bridged Cu(II) complexes of a pyridoxal Schiff base ligand 4-((E)-(2-(pyridin-2-yl)ethylimino)methyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol (LH) have been synthesized and characterized on the basis of spectroscopic, elctrochemical and structural properties. The X-ray crystal structures of the complexes reveal dual denticity of the ligand, bidenticity in the absence of a co-ligand as in complex 1, and tridenticity in the presence of a co-ligand such as SCN/N(CN)2 as in complexes 2 and 3. The complexes, though binuclear in the solid state, exist as a monomeric unit in solution due to the exceptionally long axial Cu–Ohydroxymethyl (2.4–2.5 Å) bond. All three complexes show efficient catalytic activities towards the aerial oxidation of 3,5-ditertiarybutylcatechol (DTBCH2) with kcat values of 5.38 × 104 h−1, 1.18 × 105 h−1 and 1.06 × 105 h−1 in methanol. Complexes 1 and 2 also act as a selective sulphide ion sensor with Kb values of 6.6 × 103 M−1 and 8.1 × 103 M−1, respectively, while their respective L.O.D. values are 3.4 μM and 3.2 μM.

Graphical abstract: Structural divergence in binuclear Cu(ii) pyridoxal Schiff base complexes probed by co-ligands: catecholase mimetic activity and sulphide ion sensing

Supplementary files

Article information

Article type
Paper
Submitted
10 Feb 2020
Accepted
03 Jul 2020
First published
03 Jul 2020

New J. Chem., 2020,44, 12916-12925

Structural divergence in binuclear Cu(II) pyridoxal Schiff base complexes probed by co-ligands: catecholase mimetic activity and sulphide ion sensing

M. Chakraborty, A. Mondal and S. K. Chattopadhyay, New J. Chem., 2020, 44, 12916 DOI: 10.1039/D0NJ00719F

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