A novel organic–inorganic hybrid material: production, characterization and catalytic performance for the reaction of arylaldehydes, dimedone and 6-amino-1,3-dimethyluracil

Abstract

A novel silica-based organic–inorganic hybrid material namely N,N,N′,N′-tetramethyl-N-(silica-n-propyl)-N′-sulfonic acid-ethylenediaminium chloride/mesylate ([TSSECM]) was prepared, and characterized by EDS (energy-dispersive X-ray spectroscopy), FE-SEM (field emission scanning electron microscopy), FT-IR, XRD (X-ray diffraction), TGA (thermal gravimetric analysis) and adsorption/desorption porosimetry analyses. The sizes of most particles of [TSSECM] were less than 100 nm (i.e. they were nanomaterials), and some particles had sizes more than 100 nm (up to 185 nm). The hybrid material was applied as a highly efficacious, recyclable and dual-functional catalyst for the one-pot multi-component reaction of arylaldehydes, dimedone and 6-amino-1,3-dimethyluracil under solvent-free conditions to give pyrimido[4,5-b]quinolines.