Dual functional luminescent nanoprobes for monitoring oxygen and chloride concentration changes in cells†
Abstract
A dual functional nanoprobe Pd–Q+@PDMS was proposed to simultaneously monitor Cl− and O2, leading to the determination of an average Cl− concentration of 85.7 ± 5.5 mM in lysosomes of HeLa cells. Mimicking ischemic conditions, the cells exhibited a luminescence change corresponding to a decreasing subcellular Cl− concentration.