Ln3+-Triggered self-assembly of a heterotrimer collagen mimetic peptide into luminescent nanofibers

Xiuxia Sun; Wenhua Li; Jingyuan Yu; Liting Luo; Jie Wang; Jianxi Xiao

doi:10.1039/D0CC06185A

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Ln³⁺-Triggered self-assembly of a heterotrimer collagen mimetic peptide into luminescent nanofibers†

Xiuxia Sun,^a Wenhua Li,^a Jingyuan Yu,^a Liting Luo,^b Jie Wang^b and Jianxi Xiao

*^a

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* Corresponding authors

^a State Key Laboratory of Applied Organic Chemistry, Key Laboratory of Nonferrous Metal Chemistry and Resources Utilization of Gansu Province, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000, P. R. China
E-mail: xiaojx@lzu.edu.cn

^b Key laboratory of Magnetic Resonance in Biological Systems, State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, Wuhan Institute of Physics and Mathematics, Chinese Academy of Sciences, Wuhan, China

Abstract

Type I collagen, the most abundant and arguably the most complex molecule in the human body, is an ABB heterotrimer that self-assembles to form well-defined nanofibers. We herein for the first time report the construction of peptides that could simultaneously mimic the heterotrimer composition and the self-assembly features of Type I collagen.

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Article information

DOI: https://doi.org/10.1039/D0CC06185A
Article type: Communication
Submitted: 13 Sep 2020
Accepted: 21 Oct 2020
First published: 21 Oct 2020

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Chem. Commun., 2020,56, 15141-15144

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Ln³⁺-Triggered self-assembly of a heterotrimer collagen mimetic peptide into luminescent nanofibers

X. Sun, W. Li, J. Yu, L. Luo, J. Wang and J. Xiao, Chem. Commun., 2020, 56, 15141 DOI: 10.1039/D0CC06185A

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