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An AIE probe for imaging mitochondrial SO2-induced stress and SO2 levels during heat stroke

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Abstract

A probe, MITO-TPE, was developed for imaging mitochondrial SO2 with good selectivity, high sensitivity, and a fast response time. Cell imaging indicated that SO2-induced oxidative stress may cause damage to cells through O2˙ bursting. MITO-TPE has here been used to image the misregulation of SO2 levels in mitochondria during heat stroke for the first time.

Graphical abstract: An AIE probe for imaging mitochondrial SO2-induced stress and SO2 levels during heat stroke

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Supplementary files

Article information


Submitted
27 Aug 2020
Accepted
24 Sep 2020
First published
24 Sep 2020

Chem. Commun., 2020, Advance Article
Article type
Communication

An AIE probe for imaging mitochondrial SO2-induced stress and SO2 levels during heat stroke

X. Yang, J. Tang, D. Zhang, X. Han, J. Liu, J. Li, Y. Zhao and Y. Ye, Chem. Commun., 2020, Advance Article , DOI: 10.1039/D0CC05803C

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