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Catalytic hairpin assembly mediated liposome-encoded magnetic beads for signal amplification of peroxide test strip based point-of-care testing of ricin

Abstract

Herein, we propose a new peroxide test strip (PTS) based point-of-care testing (POCT) method to detect ricin B-chain qualitatively and quantitatively by using a catalytic hairpin assembly (CHA) mediated liposome-encoded magnetic beads for signal amplification. Because it combined the CHA signal amplification and the liposome-based signal amplification, the sensitivity of this PTS based POCT method was improved significantly.

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Article information


Submitted
11 Aug 2020
Accepted
16 Oct 2020
First published
17 Oct 2020

Chem. Commun., 2020, Accepted Manuscript
Article type
Communication

Catalytic hairpin assembly mediated liposome-encoded magnetic beads for signal amplification of peroxide test strip based point-of-care testing of ricin

Q. C. Ye, M. Chen, Y. F. Li, J. J. Liu, C. Z. Huang and S. J. Zhen, Chem. Commun., 2020, Accepted Manuscript , DOI: 10.1039/D0CC05456A

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