Issue 90, 2020

Catalytic hairpin assembly mediated liposome-encoded magnetic beads for signal amplification of peroxide test strip based point-of-care testing of ricin

Abstract

Herein, we propose a new peroxide test strip (PTS) based point-of-care testing (POCT) method to detect ricin B-chain qualitatively and quantitatively by using catalytic hairpin assembly (CHA) mediated liposome-encoded magnetic beads for signal amplification. The sensitivity of this PTS based POCT method was improved significantly because it combined CHA signal amplification and liposome-based signal amplification.

Graphical abstract: Catalytic hairpin assembly mediated liposome-encoded magnetic beads for signal amplification of peroxide test strip based point-of-care testing of ricin

Supplementary files

Article information

Article type
Communication
Submitted
11 Aug 2020
Accepted
16 Oct 2020
First published
17 Oct 2020

Chem. Commun., 2020,56, 14091-14094

Catalytic hairpin assembly mediated liposome-encoded magnetic beads for signal amplification of peroxide test strip based point-of-care testing of ricin

Q. C. Ye, C. Men, Y. F. Li, J. J. Liu, C. Z. Huang and S. J. Zhen, Chem. Commun., 2020, 56, 14091 DOI: 10.1039/D0CC05456A

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