Issue 75, 2020
From the journal:

Chemical Communications

An activatable probe for detecting alcoholic liver injury via multispectral optoacoustic tomography and fluorescence imaging†

Junjie Chen,a   Yichang Fang,a   Lihe Sun, ORCID logo a   Fang Zeng ORCID logo *a  and  Shuizhu Wu ORCID logo *a  

* Corresponding authors

a State Key Laboratory of Luminescent Materials and Devices, Guangdong Provincial Key Laboratory of Luminescence from Molecular Aggregates, College of Materials Science and Engineering, South China University of Technology, Guangzhou 510640, China
E-mail: mcfzeng@scut.edu.cn, shzhwu@scut.edu.cn

Abstract

A probe has been developed for imaging alcoholic liver injury through detecting the overexpressed cytochrome P450 reductase in hypoxia in the hepatic region. Upon response to the enzyme, the activated probe displays turn-on fluorescence and near-infrared absorption and generates prominent optoacoustic signals.

Graphical abstract: An activatable probe for detecting alcoholic liver injury via multispectral optoacoustic tomography and fluorescence imaging

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Article information

DOI
https://doi.org/10.1039/D0CC04635C
Article type
Communication
Submitted
04 Jul 2020
Accepted
04 Aug 2020
First published
05 Aug 2020

Chem. Commun., 2020,56, 11102-11105

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An activatable probe for detecting alcoholic liver injury via multispectral optoacoustic tomography and fluorescence imaging

J. Chen, Y. Fang, L. Sun, F. Zeng and S. Wu, Chem. Commun., 2020, 56, 11102 DOI: 10.1039/D0CC04635C

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