Issue 76, 2020

Amplified AND logic platform for cell identification

Abstract

Herein, we developed an amplified AND logic platform (AALP) on a cell membrane, which integrated two DNA aptamers for cell recognition and localized catalytic hairpin assembly (LCHA) for signal amplification. The AALP could perform “AND” logic computing via a double-checked strategy of two biomarkers on similar cell surfaces and precisely label the target cells with an amplified fluorescence signal.

Graphical abstract: Amplified AND logic platform for cell identification

Supplementary files

Article information

Article type
Communication
Submitted
15 Jun 2020
Accepted
27 Jul 2020
First published
27 Jul 2020

Chem. Commun., 2020,56, 11267-11270

Amplified AND logic platform for cell identification

J. Wang, J. Li, S. Liu, X. Meng, X. Yang, J. Huang and K. Wang, Chem. Commun., 2020, 56, 11267 DOI: 10.1039/D0CC04159A

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