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Issue 86, 2020
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Step and redox efficient nitroarene to indole synthesis

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Abstract

Step and redox efficiencies are a rising priority in synthetic method development, in order to make synthetic processes more sustainable and more affordable. Herein, a step and redox efficient nitroarene to indole synthesis is developed, in sharp contrast to the rich literature on the construction of indoles. Elemental zinc was found to be the best terminal reductant.

Graphical abstract: Step and redox efficient nitroarene to indole synthesis

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Article information


Submitted
06 May 2020
Accepted
13 Jul 2020
First published
06 Oct 2020

This article is Open Access

Chem. Commun., 2020,56, 13185-13188
Article type
Communication

Step and redox efficient nitroarene to indole synthesis

B. Özkaya, C. L. Bub and F. W. Patureau, Chem. Commun., 2020, 56, 13185
DOI: 10.1039/D0CC03258A

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