Issue 46, 2020
From the journal:

Chemical Communications

Wettability read-out strategy for aptamer target binding based on a recognition/hydrophobic bilayer surface†

Yunfei Fan,a   Yahang Xie,a   Zhen Zhao,a   Yang Zhao,b   Rui Yu,a   Xiang-yang Liu, ORCID logo a   Youhui Lin ORCID logo a  and  Changxu Lin ORCID logo *a  

* Corresponding authors

a Research Institute for Biomimetics and Soft Matter, Fujian Provincial Key Laboratory for Soft Functional Materials Research, College of Physical Science and Technology, Xiamen University, 9 Zengcuoan West Road, 361005 Xiamen, China
E-mail: lincx@xmu.edu.cn

b Institute of Forensic Science, Ministry of Public Security, Beijing, China

Abstract

We established a wettability read-out strategy for an aptasensor with a bilayer surface, using hydrophobicity reduction as the signal. The signal was induced by a fracture of the nanoneedle layer resulting from recognition by the supporting aptamer layer. The kinetics and influencing factors of this process were investigated with time curves.

Graphical abstract: Wettability read-out strategy for aptamer target binding based on a recognition/hydrophobic bilayer surface

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Article information

DOI
https://doi.org/10.1039/D0CC01936D
Article type
Communication
Submitted
14 Mar 2020
Accepted
28 Apr 2020
First published
29 Apr 2020

Chem. Commun., 2020,56, 6225-6228

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Wettability read-out strategy for aptamer target binding based on a recognition/hydrophobic bilayer surface

Y. Fan, Y. Xie, Z. Zhao, Y. Zhao, R. Yu, X. Liu, Y. Lin and C. Lin, Chem. Commun., 2020, 56, 6225 DOI: 10.1039/D0CC01936D

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