Luminescent molecules towards precise cellular event regulation

Ming Hu; Qinyu Han; Linna Lyu; Yan Tong; Shuo Dong; Zhi-Heng Loh; Bengang Xing

doi:10.1039/D0CC01923B

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Luminescent molecules towards precise cellular event regulation†

Ming Hu,

^a Qinyu Han,^a Linna Lyu,^a Yan Tong,^b Shuo Dong,^a Zhi-Heng Loh^a and Bengang Xing

*^a

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* Corresponding authors

^a Division of Chemistry and Biological Chemistry, School of Physical & Mathematical Sciences, Nanyang Technological University, 21 Nanyang link, Singapore
E-mail: bengang@ntu.edu.sg

^b CBIS Confocal Microscopy Laboratory, National University of Singapore, Singapore, Singapore

Abstract

A unique lanthanide complex which responds to near-infrared (NIR) stimulation was developed for remote regulation of cellular events. This molecule can be localized specifically on the cell surface. Upon NIR stimulation, strong emission of the complex can successfully modulate the activities of light-gated membrane channels and regulate the ion flux in vivo.

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Article information

DOI: https://doi.org/10.1039/D0CC01923B
Article type: Communication
Submitted: 13 Mar 2020
Accepted: 23 Jul 2020
First published: 24 Jul 2020

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Chem. Commun., 2020,56, 10231-10234

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Luminescent molecules towards precise cellular event regulation

M. Hu, Q. Han, L. Lyu, Y. Tong, S. Dong, Z. Loh and B. Xing, Chem. Commun., 2020, 56, 10231 DOI: 10.1039/D0CC01923B

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Chemical Communications

Luminescent molecules towards precise cellular event regulation†

Abstract

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Luminescent molecules towards precise cellular event regulation

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