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A terbium(iii) luminescent ATCUN-based peptide sensor for selective and reversible detection of copper(ii) in biological media

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Abstract

The measurement of exchangeable Cu2+ levels in biological samples is gaining interest in the context of copper-related pathologies. Here, we report a Tb3+ luminescent turn-off sensor for Cu2+ based on the specific and suitable-affinity Xxx-Zzz-His (ATCUN) peptide motif, enabling Cu2+ detection in the presence of a biological fluorescent background.

Graphical abstract: A terbium(iii) luminescent ATCUN-based peptide sensor for selective and reversible detection of copper(ii) in biological media

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Article information


Submitted
07 Feb 2020
Accepted
23 Mar 2020
First published
26 Mar 2020

Chem. Commun., 2020, Advance Article
Article type
Communication

A terbium(III) luminescent ATCUN-based peptide sensor for selective and reversible detection of copper(II) in biological media

E. Falcone, P. Gonzalez, L. Lorusso, O. Sénèque, P. Faller and L. Raibaut, Chem. Commun., 2020, Advance Article , DOI: 10.1039/D0CC01007C

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